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|Title:||Functional properties of extruded and tubular films of sorghum starch-based glycerol and Yucca Schidigera extract|
|Abstract:||The single-nucleotide polymorphisms (SNPs) in the human DNase I gene (DNASE1) might be involved in susceptibility to some common diseases; however, only limited population data are available. Further, the effects of these SNPs on in vivo DNase I activity remain unknown. The genotype and haplotype of all the SNPs in DNASE1 were determined in 3 ethnic groups including 14 populations using newly developed methods. Together with our previous data on the nonsynonymous SNPs, two major haplotypes based on the five exonic SNPs were identified; genetic diversity in the Asian population was low. Among 10 SNPs, other than exonic SNPs in the gene, only 3 were polymorphic among all the populations. Haplotype distribution, based on all the polymorphic SNPs, was clarified to be generally varied in an ethnic-dependent manner. Thus, the genetic aspects of DNASE1 with regard to all the SNPs in wide-ranging ethnic groups could be first demonstrated. Further, there was no correlation of all the polymorphic SNPs other than nonsynonymous ones with serum DNase I activity levels. Polymorphic SNPs other than the exonic SNPs might not be directly related to common diseases through alterations in in vivo levels of the activity. " Copyright 2011, Mary Ann Liebert, Inc.",,,,,,"10.1089/dna.2010.1120",,,"http://hdl.handle.net/20.500.12104/41625","http://www.scopus.com/inward/record.url?eid=2-s2.0-79953240248&partnerID=40&md5=272c1e865e225571d447b2984f9eaf0c",,,,,,"4",,"DNA and Cell Biology",,"205|
WOS",,,,,,,,,,,,"Functional and genetic survey of all known single-nucleotide polymorphisms within the human deoxyribonuclease I gene in wide-ranging ethnic groups",,"Article" "43372","123456789/35008",,,,"Velasco Ugalde, E.",,"1991",,,,,,,,,,"0187-8190","http://hdl.handle.net/20.500.12104/41593",,,"Español",,,,"20",,"Revista mexicana de comunicación",,"15-16",,"4",,"CLASE",,,,,,,,"Medios de comunicación masiva",,,,"El libre comercio por la radio mexicana",,"journalArticle" "43409","123456789/35008",,"Rodríguez-Castellanos, W., Centro de Investigación y de Estudios Avanzados, Instituto Politécnico Nacional, Unidad Querétaro, Fraccionamiento Real de Juriquilla, Libramiento Norponiente #2000, C.P. 76230 Santiago de Querétaro, Qro., Mexico; Martínez-Bustos, F., Centro de Investigación y de Estudios Avanzados, Instituto Politécnico Nacional, Unidad Querétaro, Fraccionamiento Real de Juriquilla, Libramiento Norponiente #2000, C.P. 76230 Santiago de Querétaro, Qro., Mexico; Jiménez-Arévalo, O., Universidad Aeronáutica de Querétaro, Tequisquiapan No. 22154, Carretera Estatal 200 Querétaro, C.P. 76270 Colón, Querétaro, Mexico; González-Núñez, R., Departamento de Ingeniería Química, Universidad de Guadalajara, Blvd. Marcelino García Barragán No. 1451, C.P. 44430 Guadalajara, Jalisco, Mexico; Galicia-García, T., Centro de Investigación y de Estudios Avanzados, Instituto Politécnico Nacional, Unidad Querétaro, Fraccionamiento Real de Juriquilla, Libramiento Norponiente #2000, C.P. 76230 Santiago de Querétaro, Qro., Mexico",,"Rodriguez-Castellanos, W.
Galicia-García, T.",,"2013",,"The objective of this research was to evaluate the effects of processing parameters on functional properties of extruded and tubular films. Four formulations of sorghum starch, with glycerol, and Yucca Schidigera extract, were used to prepare extruded and tubular films. Based on mechanical testing the formulation of 78.5% sorghum starch, 20% glycerol and 1.5% Yucca Schidigera extract, with 20% moisture content, showed the best mechanical properties and was selected to evaluate the effect of barrel temperature and screw speed during the fabrication of tubular films. Films were characterized through mechanical testing, scanning electron microscopy, water vapor permeability, water disintegration index, density and thickness. " 2012.
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